Antiovarian antibodies do not correlate with the presence or severity of oophritis and do not predict when ovarian failure will occur, so the measuring of these antibodies is not recommended

Steroid producing cells (hillar cells, granulosa cells, theca internal and corpus luteum). Autoantibodies to steroid producing cells are widely present in POF associated with Addison’s disease (75). In autoimmune oophoritis, lymphatic infiltration is confined to secondary and antral follicles that have theca cells. This finding shows that steroid producing cells express the antigens that stimulate the immune response (74).

3?-hydroxysteroid dehydrogenase (3?-HSD). Continue reading Antiovarian antibodies in POF have been reported in several studies, but their specificity and pathogonomic roles are questionable →